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P9620
Sigma
Puromycin dihydrochloride
Ready Made Solution, from Streptomyces alboniger, 10 mg/mL in H2O, 0.2 μm filtered
| CAS Number: | 58-58-2 |
| EC Number: | 200-387-8 |
| MDL number: | MFCD00067313 |
Description
| Biochem/physiol Actions | Puromycin inhibits the growth of a wide range of eukaryotic and prokaryotic cells by interfering with protein synthesis. It allows the selection of cells expressing the pac gene. |
| Suitability | Tested on HeLa cells for cell growth arrest and selection of cells after transfection of the pac resistance gene. |
Properties
| biological source | from Streptomyces alboniger |
| sterility | 0.2 μm filtered |
| assay | >98% (HPLC) |
| concentration | 10 mg/mL in H2O |
| suitability | cell culture tested |
| shipped in | wet ice |
| storage temp. | −20°C |
Safety
References
| reference | Tabuchi, I. Biochem. Biophys. Res. Commun. 23, 2-5, (2003) |
| Eyckerman, S., et al. Nat. Cell Biol. 3, 1114-1116, (2001) |
